| Species/Subspecies:
|
Candida albicans |
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| Categories:
|
Animal pathogen; human pathogen |
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| Etymology:
|
Genus name: white.
Species epithet: be white. |
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| Significance: | [Very important]
|
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| Geographic distribution:
|
Has a global distribution |
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| Taxonomy:
|
| Phylum | Class | Order | Family | Genus |
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| Ascomycota | Saccharomycetes | Saccharomycetales | Saccharomycetaceae | Candida |
|
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| | |
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| Macromorphology (smell):
| C. albicans is dimorphic and the colonies are creamish white, opaque and circular, when it grows like yeast on an agar plate. |
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| Micromorphology:
| C. albicans is a kind of yeast that forms so-called pseudohyphae. |
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| Reproduction: | Man trodde länge att C. albicans var stabilt diploid och enbart förökar sig asexuellt genom avknoppning liksom många andra jästsvampar. Man har dock kunnat visa att denna svamp kan övergå till att vara haploid. De haploida cellerna kan sedan tillsammans med andra haploida celler av motsatt parningstyp bilda diploida celler (s.k. klamydiaspores). |
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| Enzymes:
| Urease + |
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| Spec. Char.:
| |
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| Reservoir:
| Plant material and the gut of animals and humans. |
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| Disease/effect:
| Belongs to the normal flora, but may cause severe infections in immuncompromised individuals.
|
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| Virulence Factors:
| Extracellular and cytotoxic phospholipases and proteases. Candida spp. can vary the expression of surface antigens, which allows them to escape the immune defense of the host animal. C. albicans is the most common fungus that can be isolated from biofilms. |
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| Diagnostics:
| Presence of C. albicans in the tissue lesion must be shown by direct examination or histological evaluation. |
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| Genome Sequence:
|
| ACC-No GenBank | Strain/Isolate | # of chrom | Size (Mbp) | Ref |
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| GCF_000182965 | SC5314 | 8 | 14.3 | # 1 |
C. albicans kan vara haploid, diploid eller tetraploid. The genome sequence refers to the haploid form.
|
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| Mitochondrial DNA sequence:
|
| ACC-No GenBank | Strain/Isolate | Number of BP | Ref |
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| NC_018046 | L757 | 33 928 | # 59 |
Circular DNA
|
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| 18S rRNA Seq:
|
| ACC-No GenBank | Strain/Isolate | Number of NT |
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| NG_070791 | CBS 562 | 1787 |
|
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| ITS regions:
|
| ACC-No GenBank | Strain/Isolate | Number of NT | Genes |
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| NR_125332 | CBS 562TM | 495 | 18S rRNA, ITS 1, 5.8S rRNA, ITS 2, 28S rRNA |
|
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| Taxonomy/phylogeny:
|
More than 200 species have been described within genus Candida. |
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| Reference(s):
| No. 4, 16, 25 |
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| Link:
| Candida Genome Database |
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| Updated: | 2022-06-22 |
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