| Species/Subspecies:
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Malassezia pachydermatis |
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| Categories:
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Animal pathogen; human pathogen |
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| Etymology:
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Genus name: Named after the French scientist Louis-Charles Malassez.
Species epithet: Greek for thick-skin. |
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| Alternative Species Name(s): | Pityrosporum malassez |
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| Significance: | [Very important]
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| Taxonomy:
|
| Phylum | Class | Order | Family | Genus |
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| Basidiomycota | Exobasidiomycetes | Malasseziales | Malasseziaceae | Malassezia |
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| | |
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Macromorphology (smell):
 | The colonies are creamy and yellowish and smooth to wrinkled and convex with an edge, which has a slightly lobed appearance. M. pachydermatis can be cultivated on Sabaroud agar. |
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| Micromorphology:
| The size of the ovoidal cells are 3.0–6.5 x 2.5 µm. |
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| Reproduction: | |
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| Enzymes:
| Catalase + |
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| Spec. Char.:
| Optimal growth temperature is 30-37°C. M pachydermatis is the only species in its genus that grows in the absence of fatty acids, although growth is stimulated by fatty acids. |
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| Reservoir:
| Can be found in the normal flora of the skin healthy mammals. |
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| Disease/effect:
| | Hosts/substrate | Disease/effect | Clinical picture or result |
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| Dog | Otitis externa | Severe itching, head shaking as well as bad smell and reddish-brown waxy deposits in the ear canal. | | Dog | Seborrhoeic dermatitis | Areas of the skin along the back, which are rich in sebaceous glands, suffer from redness and white scales (dandruff) that come off. | | Cat | Otitis externa can affect cats, but it is rare. | See Dog | | Human | Seborrhoeic dermatitis in infants and immunocompromised individuals. | Reddening skin eczema, which scales. |
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| Virulence Factors:
| Chondroitin-sulfatase, hyaluronidase, phospholipase and proteinase, which are tissue degrading enzymes. |
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| Diagnostics:
| Cytological examination of the suspected area of the animal. |
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| Genome Sequence:
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| ACC-No GenBank | Strain/Isolate | # of chrom | Size (Mbp) | Ref |
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| GCF_001278385 | CBS 1879 | 6 | 08,1 | # 3 |
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| 18S rRNA Seq:
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| ACC-No GenBank | Strain/Isolate | Number of NT |
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| EU192366 | ATCC 14522 | 1557 |
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| ITS regions:
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| ACC-No GenBank | Strain/Isolate | Number of NT | Genes |
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| NR_126114 | CBS 1879TM | 755 | ITS 1, 5.8S rRNA, ITS 2, 28S rRNA |
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| Taxonomy/phylogeny:
|
About 20 species have been described within this genus. |
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| Comment: | The disease is zoonotic. |
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| Reference(s):
| No. 20 |
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| Updated: | 2022-06-22 |
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