Species/Subspecies:
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Histoplasma capsulatum subsp. capsulatum |
Category:
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Animal pathogen |
Etymology:
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Genus name: web, formed from the loom.
Species epithet: encapsulated. |
Alternative Species Name(s): | Ajellomyces capsulatus |
Significance: | [Of minor importance]
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Taxonomy:
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Phylum | Class | Order | Family | Genus |
Ascomycota | Eurotiomycetes | Onygenales | Ajellomycetaceae | Histoplasma |
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Macromorphology (smell):
| H. capsulatum subsp. capsulatum is a thermally dimorhic fungus, which grows as a yeast in warm-blooded animals. |
Micromorphology:
| Like mould: Septated hyphae with small conidia and sunflower-like macroconidia (10-15 µm in diameter).
Like Yeast: The yeast cells are oval and 2-5 µm in diameter. |
Reproduction: | This fungus has both asexual and sexual reproduction and it is heterothallic. |
Spec. Char.:
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Reservoir:
| Soil and particularly when is is contaminated with bird or bat droppings. |
Disease/effect:
| Hosts/substrate | Disease/effect | Clinical picture or result |
Dogs and cats | Systemic histplasmosis | Usually asymptomatic, but granulomatous lesions may occur in the lungs. Disseminated disease in immune compromised individuals has been reported in both species. | Humans | Histoplasmosis (cave disease) | The disease is usually subclinical, but can cause symptoms similar to pneumonia in immune compromised individuals. Erythematous skin changes can occur in children and adults, who are exposed to large amounts of this fungus. |
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Genome Sequence:
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ACC-No GenBank | Strain/Isolate | # of chrom | Size (Mbp) |
GCA_000149585 | NAm1 | | 30.6 |
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18S rRNA Seq:
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ACC-No GenBank | Strain/Isolate | Number of NT |
KY792633 | UZ_597_16 | 641 |
Partial sequence
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ITS regions:
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ACC-No GenBank | Strain/Isolate | Number of NT | Genes |
NR_149341 | CBS 136.72TM | 522 | ITS 1, 5.8S rRNA, ITS 2 |
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Taxonomy/phylogeny:
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Updated: | 2022-06-22 |