Species/Subspecies: Histoplasma capsulatum subsp. capsulatum
Category: Animal pathogen
Etymology: Genus name: web, formed from the loom.
Species epithet: encapsulated.
Alternative Species Name(s):Ajellomyces capsulatus
Significance:  [Of minor importance]   
Macromorphology (smell): H. capsulatum subsp. capsulatum is a thermally dimorhic fungus, which grows as a yeast in warm-blooded animals.
Micromorphology: Like mould: Septated hyphae with small conidia and sunflower-like macroconidia (10-15 µm in diameter).
Like Yeast: The yeast cells are oval and 2-5 µm in diameter.
Reproduction:This fungus has both asexual and sexual reproduction and it is heterothallic.
Spec. Char.:
Reservoir: Soil and particularly when is is contaminated with bird or bat droppings.
Hosts/substrateDisease/effectClinical picture or result
Dogs and catsSystemic histplasmosisUsually asymptomatic, but granulomatous lesions may occur in the lungs. Disseminated disease in immune compromised individuals has been reported in both species.
HumansHistoplasmosis (cave disease)The disease is usually subclinical, but can cause symptoms similar to pneumonia in immune compromised individuals. Erythematous skin changes can occur in children and adults, who are exposed to large amounts of this fungus.
Genome Sequence:
ACC-No GenBankStrain/Isolate# of chromSize (Mbp)
GCA_000149585 NAm1  30.6 

Mitochondrial DNA sequence:  -
18S rRNA Seq:
ACC-No GenBankStrain/IsolateNumber of NT
KY792633 UZ_597_16 641 
Partial sequence

ITS regions:
ACC-No GenBankStrain/IsolateNumber of NTGenes
NR_149341 CBS 136.72TM 522 ITS 1, 5.8S rRNA, ITS 2 


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Swedish University of Agricultural Sciences