Species/Subspecies: Blastomyces dermatitidis
Categories: Animal pathogen; human pathogen
Etymology: Genus name: germ fungus.
Species epithet: of skin.
Alternative Species Name(s):Ajellomyces dermatitidis är namnet på teleomorfen av denna svamp och bör alltså inte användas.
Significance:This fungus is of minor importance in Sweden, but occurs in eastern North America and sporadically in India and the Middle East.
  [Of minor importance]   
Geographic distribution: The fungus is common in eastern North America and is rare in Africa, the Arabian Peninsula and India.
Taxonomy:
PhylumClassOrderFamilyGenus
AscomycotaEurotiomycetesOnygenalesAjellomycetaceaeBlastomyces
 
Macromorphology (smell):
Micromorphology: Like mould: Oval or pear-shaped conidia (2-10 µm in diameter) are formed on conidiophores or directly on septated hyphae.
Like yeast: The yeast cells are thick-walled and 8-10 µm in diameter.
Reproduction:
Spec. Char.: This is a thermally dimorhic fungus.
Reservoir: Moist and acid soil, which is enriched with organic matter.
Disease/effect:
Hosts/substrateDisease/effectClinical picture or result
Dog, rarely also cat and possibly other animal species.BlastomycosisInfection in the lungs, which may spread to the skin and other tissues.
HumansBlastomycosisInfection in the lungs, which may spread to the skin and other tissues.
Virulence Factors: BAD 1 (Blastomyces adhesin 1), which is a surface protein that promotes adhesion to cells in the respiratory system and modulates the immune system of the host animal.
Diagnostics: There are PCR systems for detection and identification of B. dermatitidis.
Genome Sequence:
ACC-No GenBankStrain/Isolate# of chromSize (Mbp)
GCA_000003525 ER-3  66.3 

18S rRNA Seq:
ACC-No GenBankStrain/IsolateNumber of NT
M63096 ATCC 26199 1800 

ITS regions:
ACC-No GenBankStrain/IsolateNumber of NTGenes
NR_163503 UAMH 3538TM 664 ITS 1, 5.8S rRNA, ITS 2, 28S rRNA 

Taxonomy/phylogeny:
Reference(s): No. 50
Link: Blastomyces dermatitidis - An Overview
Updated:2022-06-22

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Swedish University of Agricultural Sciences