Species/Subspecies:
|
Blastomyces dermatitidis |
Categories:
|
Animal pathogen; human pathogen |
Etymology:
|
Genus name: germ fungus.
Species epithet: of skin. |
Alternative Species Name(s): | Ajellomyces dermatitidis är namnet på teleomorfen av denna svamp och bör alltså inte användas. |
Significance: | This fungus is of minor importance in Sweden, but occurs in eastern North America and sporadically in India and the Middle East.
[Of minor importance]
|
Geographic distribution:
|
The fungus is common in eastern North America and is rare in Africa, the Arabian Peninsula and India. |
Taxonomy:
|
Phylum | Class | Order | Family | Genus |
Ascomycota | Eurotiomycetes | Onygenales | Ajellomycetaceae | Blastomyces |
|
---|
| |
Macromorphology (smell):
| |
Micromorphology:
| Like mould: Oval or pear-shaped conidia (2-10 µm in diameter) are formed on conidiophores or directly on septated hyphae.
Like yeast: The yeast cells are thick-walled and 8-10 µm in diameter. |
Reproduction: | |
Spec. Char.:
| This is a thermally dimorhic fungus. |
Reservoir:
| Moist and acid soil, which is enriched with organic matter. |
Disease/effect:
| Hosts/substrate | Disease/effect | Clinical picture or result |
Dog, rarely also cat and possibly other animal species. | Blastomycosis | Infection in the lungs, which may spread to the skin and other tissues. | Humans | Blastomycosis | Infection in the lungs, which may spread to the skin and other tissues. |
|
Virulence Factors:
| BAD 1 (Blastomyces adhesin 1), which is a surface protein that promotes adhesion to cells in the respiratory system and modulates the immune system of the host animal. |
Diagnostics:
| There are PCR systems for detection and identification of B. dermatitidis. |
Genome Sequence:
|
ACC-No GenBank | Strain/Isolate | # of chrom | Size (Mbp) |
GCA_000003525 | ER-3 | | 66.3 |
|
18S rRNA Seq:
|
ACC-No GenBank | Strain/Isolate | Number of NT |
M63096 | ATCC 26199 | 1800 |
|
ITS regions:
|
ACC-No GenBank | Strain/Isolate | Number of NT | Genes |
NR_163503 | UAMH 3538TM | 664 | ITS 1, 5.8S rRNA, ITS 2, 28S rRNA |
|
Taxonomy/phylogeny:
|
|
Reference(s):
| No. 50 |
Link:
| Blastomyces dermatitidis - An Overview |
Updated: | 2022-06-22 |