|| Malassezia pachydermatis|
||Animal pathogen; human pathogen|
||Genus name: Named after the French scientist Louis-Charles Malassez.
Species epithet: Greek for thick-skin.
|Alternative Species Name(s):||Pityrosporum malassez|
|Significance:|| [Very important]
|The colonies are creamy and yellowish and smooth to wrinkled and convex with an edge, which has a slightly lobed appearance. M. pachydermatis can be cultivated on Sabaroud agar.
||The size of the ovoidal cells are 3.0–6.5 x 2.5 µm.
||Optimal growth temperature is 30-37°C. M pachydermatis is the only species in its genus that grows in the absence of fatty acids, although growth is stimulated by fatty acids.|
||Can be found in the normal flora of the skin healthy mammals.|
|Hosts/substrate||Disease/effect||Clinical picture or result|
|Dog||Otitis externa||Severe itching, head shaking as well as bad smell and reddish-brown waxy deposits in the ear canal. |
|Dog||Seborrhoeic dermatitis||Areas of the skin along the back, which are rich in sebaceous glands, suffer from redness and white scales (dandruff) that come off. |
|Cat||Otitis externa can affect cats, but it is rare.||See Dog|
|Human||Seborrhoeic dermatitis in infants and immunocompromised individuals.||Reddening skin eczema, which scales. |
||Chondroitin-sulfatase, hyaluronidase, phospholipase and proteinase, which are tissue degrading enzymes.|
||Cytological examination of the suspected area of the animal.|
|ACC-No GenBank||Strain/Isolate||# of chrom||Size (Mbp)||Ref|
|GCF_001278385 ||CBS 1879 ||6 ||08,1 ||# 3|
|Mitochondrial DNA sequence:
|18S rRNA Seq:
|ACC-No GenBank||Strain/Isolate||Number of NT|
|EU192366 ||ATCC 14522 ||1557 |
|ACC-No GenBank||Strain/Isolate||Number of NT||Genes|
|NR_126114 ||CBS 1879TM ||755 ||ITS 1, 5.8S rRNA, ITS 2, 28S rRNA |
||About 20 species have been described within this genus.
|Comment:||The disease is zoonotic.|