| Species/Subspecies:
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Paecilomyces niveus |
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| Categories:
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Toxic for animals; toxic for humans; of practical use; spoilage organism |
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| Etymology:
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| Alternative Species Name(s): | Byssochlamys nivea |
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| Significance: | This fungus is an important food spoilage organism.
[Important]
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| Taxonomy:
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| Phylum | Class | Order | Family | Genus |
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| Ascomycota | Eurotiomycetes | Eurotiales | Trichocomaceae | Paecilomyces |
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| | |
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Macromorphology (smell):
 | The colonies are white, wooly and powdery. |
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Micromorphology:
   | P. niveus is homotallic and can produce conidia, ascospores and chlamydospores (see Figs 61:2-4). |
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| Reproduction: | |
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| Spec. Char.:
| This fungus, like other fungi of the genus Paecilomyces, can grow under harsh conditions, e.g. on leather in alcohol and under low oxygen pressure. Ascospores ofP. niveus survives in temperatures up to 90°C. |
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| Disease/effect:
| | Hosts/substrate | Disease/effect | Clinical picture or result |
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| Fruits (apples) | Paecilomyces rot | Brown spots with white protruding hyphae. | | Silages (feed) | Spoilage | Spoilage and degradation of the substrate | | Humans and animals | Mycotoxicosis | Nausea, infections, and diarrhea |
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| Virulence Factors:
| The mycotoxins patulin and mycophenolic acid. |
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| Genome Sequence:
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| ACC-No GenBank | Strain/Isolate | # of chrom | Size (Mbp) |
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| GCA_003116535 | Cornell orchards no. 7 | | 36.0 |
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| 18S rRNA Seq:
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| ACC-No GenBank | Strain/Isolate | Number of NT |
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| NG_061072 | CBS:100.11RM | 1598 |
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| ITS regions:
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| ACC-No GenBank | Strain/Isolate | Number of NT | Genes |
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| NR_144910 | CBS 100.11RM | 566 | ITS 1, 5.8S rRNA, ITS 2, 28S rRNA |
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| Taxonomy/phylogeny:
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| Practical use: | Used for the production of mycophenolic acid, which is an immunosuppressive drug, which is used to prevent rejection after a transplant and to treat autoimmune diseases. |
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| Reference(s):
| No. 86, 87 |
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| Updated: | 2022-12-14 |
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