Species/Subspecies: Paecilomyces niveus
Categories: Toxic for animals; toxic for humans; of practical use; spoilage organism
Alternative Species Name(s):Byssochlamys nivea
Significance:This fungus is an important food spoilage organism.
Macromorphology (smell):
Paecilomyces niveus 
The colonies are white, wooly and powdery.
Paecilomyces niveusPaecilomyces niveusPaecilomyces niveus
P. niveus is homotallic and can produce conidia, ascospores and chlamydospores (see Figs 61:2-4).
Spec. Char.: This fungus, like other fungi of the genus Paecilomyces, can grow under harsh conditions, e.g. on leather in alcohol and under low oxygen pressure. Ascospores ofP. niveus survives in temperatures up to 90°C.
Hosts/substrateDisease/effectClinical picture or result
Fruits (apples)Paecilomyces rotBrown spots with white protruding hyphae.
Silages (feed)SpoilageSpoilage and degradation of the substrate
Humans and animalsMycotoxicosisNausea, infections, and diarrhea
Virulence Factors: The mycotoxins patulin and mycophenolic acid.
Genome Sequence:
ACC-No GenBankStrain/Isolate# of chromSize (Mbp)
GCA_003116535 Cornell orchards no. 7  36.0 

18S rRNA Seq:
ACC-No GenBankStrain/IsolateNumber of NT
NG_061072 CBS:100.11RM 1598 

ITS regions:
ACC-No GenBankStrain/IsolateNumber of NTGenes
NR_144910 CBS 100.11RM 566 ITS 1, 5.8S rRNA, ITS 2, 28S rRNA 

Practical use:Used for the production of mycophenolic acid, which is an immunosuppressive drug, which is used to prevent rejection after a transplant and to treat autoimmune diseases.
Reference(s): No. 86, 87

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